Date issued: 01/12/23
Effective January 1, 2023 a new surveillance case definition for multsystem inflammatory syndrome in children (MIS-C) was implemented for reproting cases of MIS-C.
MIS-C is a rare but severe complication in children and young adults infected with SARS-CoV-2 the virus that causes COVID-19.
The new case definition criteria can be viewed at Information for Healthcare Providers about Multisystem Inflammatory Syndrome in Children (MIS-C) CDC.
Key Changes to the Definition:
1. No required duration of subjective or measured fever.
2. A requirement of C-reactive protein greater than 3.0mg/dl to indicate systematic inflammation.
3. Adjustments to criteria of organ system involvement to include addition of shock as a separate category and elimination of respiratory, neurologic and renal criteria.
4. A new requirement on timing of a positive SARS-CoV-2 laboratory testing within 60 days of MIS-C illness.